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  <xs:element id="cron_CronosGrowingCompanyInc.Member" abstract="true" name="CronosGrowingCompanyInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_ThreeMajorCustomersMember" abstract="true" name="ThreeMajorCustomersMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_StockIssuedDuringPeriodValueResearchAndDevelopmentMilestones" abstract="false" name="StockIssuedDuringPeriodValueResearchAndDevelopmentMilestones" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CBGVALicensingAgreementMember" abstract="true" name="CBGVALicensingAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OneMajorCustomerMember" abstract="true" name="OneMajorCustomerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cron_CollaborativeArrangementTermOfAgreement" abstract="false" name="CollaborativeArrangementTermOfAgreement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cron_SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsAndVestedInPeriod" abstract="false" name="SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsAndVestedInPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="cron_CannasoulAnalyticsLtdMember" abstract="true" name="CannasoulAnalyticsLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_A2015StockOptionPlanMember" abstract="true" name="A2015StockOptionPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_EffectiveIncomeTaxRateReconciliationCapitalGainFinancialLiabilitiesAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationCapitalGainFinancialLiabilitiesAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_LivWellHoldingsIncMember" abstract="true" name="LivWellHoldingsIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_SensitivityAnalysisOfCarryingValueNetAssetsImpactOf10PercentChangeInExchangeRate" abstract="false" name="SensitivityAnalysisOfCarryingValueNetAssetsImpactOf10PercentChangeInExchangeRate" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FiniteLivedIntangibleAssetsAccumulatedImpairment" abstract="false" name="FiniteLivedIntangibleAssetsAccumulatedImpairment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CapitalGainRelinquishmentOfWarrant" abstract="false" name="CapitalGainRelinquishmentOfWarrant" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CBGALicensingAgreementMember" abstract="true" name="CBGALicensingAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_U.S.DistrictCourtofEasternDistrictofNewYorkVs.CronosMember" abstract="true" name="U.S.DistrictCourtofEasternDistrictofNewYorkVs.CronosMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_FairValueRecurringBasisUnobservableInputReconciliationNetDerivativeAssetLiabilityGainLossStatementOfOtherComprehensiveIncomeExtensibleListNotDisclosedFlag" abstract="false" name="FairValueRecurringBasisUnobservableInputReconciliationNetDerivativeAssetLiabilityGainLossStatementOfOtherComprehensiveIncomeExtensibleListNotDisclosedFlag" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_DeferredTaxAssetsShareIssuanceCost" abstract="false" name="DeferredTaxAssetsShareIssuanceCost" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DeferredTaxAssetsDebtIssuanceCosts" abstract="false" name="DeferredTaxAssetsDebtIssuanceCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CollaborativeArrangementPercentageOfProfitsToBeReceived" abstract="false" name="CollaborativeArrangementPercentageOfProfitsToBeReceived" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_PeaceNaturalsReportingUnitMember" abstract="true" name="PeaceNaturalsReportingUnitMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_PreemptiveRightsMember" abstract="true" name="PreemptiveRightsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CronosIsraelG.S.CultivationsLtd.Member" abstract="true" name="CronosIsraelG.S.CultivationsLtd.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CannasoulCollaborationLoanMember" abstract="true" name="CannasoulCollaborationLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopmentExpense" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationResearchAndDevelopmentExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationOtherNonoperatingIncomeExpense" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationOtherNonoperatingIncomeExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_IsraeliCodesLicensingAgreementsMember" abstract="true" name="IsraeliCodesLicensingAgreementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_LiabilityClassifiedAwardsMember" abstract="true" name="LiabilityClassifiedAwardsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DeferredTaxLiabilitiesOperatingLeaseRightOfUseAsset" abstract="false" name="DeferredTaxLiabilitiesOperatingLeaseRightOfUseAsset" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_IntangibleAssetsAccumulatedImpairmentImpairmentInPeriod" abstract="false" name="IntangibleAssetsAccumulatedImpairmentImpairmentInPeriod" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CannabisPurchasesMember" abstract="true" name="CannabisPurchasesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_RestOfWorldSegmentMember" abstract="true" name="RestOfWorldSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_StockIssuedDuringPeriodValueTopupRightsExercised" abstract="false" name="StockIssuedDuringPeriodValueTopupRightsExercised" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FinancingReceivableInterestRateStatedPercentage" abstract="false" name="FinancingReceivableInterestRateStatedPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_FinancingReceivableCreditLossExpenseReversalIncludingTransferredIntoInvestment" abstract="false" name="FinancingReceivableCreditLossExpenseReversalIncludingTransferredIntoInvestment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ClassOfWarrantOrRightNumberOfWarrantsIssued" abstract="false" name="ClassOfWarrantOrRightNumberOfWarrantsIssued" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="cron_AccruedIncomeAndSalesAndExciseTaxesPayableCurrent" abstract="false" name="AccruedIncomeAndSalesAndExciseTaxesPayableCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CronosGroupInc.Member" abstract="true" name="CronosGroupInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_AccruedLiabilitiesPolicyPolicyTextBlock" abstract="false" name="AccruedLiabilitiesPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:textBlockItemType"/>
  <xs:element id="cron_CollaborativeArrangementPercentageOfProfitsToBeReceivedTriggeringEventSubsequentToMaximumPercentageOfAmountsAdvancedBeingMet" abstract="false" name="CollaborativeArrangementPercentageOfProfitsToBeReceivedTriggeringEventSubsequentToMaximumPercentageOfAmountsAdvancedBeingMet" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_CannabisGermplasmSupplyAgreementMember" abstract="true" name="CannabisGermplasmSupplyAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cron_OneVendorMember" abstract="true" name="OneVendorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_EffectiveIncomeTaxRateReconciliationExpectedIncomeTaxExpenseRecoveryAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationExpectedIncomeTaxExpenseRecoveryAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CannabisExtractsMember" abstract="true" name="CannabisExtractsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_MergerAgreementThresholdOwnershipPercentage" abstract="false" name="MergerAgreementThresholdOwnershipPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_ImpairmentOfIntangibleAssetFiniteLivedStatementOfIncomeOrComprehensiveIncomeExtensibleEnumerationNotDisclosedFlag" abstract="false" name="ImpairmentOfIntangibleAssetFiniteLivedStatementOfIncomeOrComprehensiveIncomeExtensibleEnumerationNotDisclosedFlag" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_TopupRightsMember" abstract="true" name="TopupRightsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_NumberOfSeatsOnBoardOfDirectors" abstract="false" name="NumberOfSeatsOnBoardOfDirectors" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="cron_VituraMember" abstract="true" name="VituraMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_IndefiniteLivedIntangibleAssetsGross" abstract="false" name="IndefiniteLivedIntangibleAssetsGross" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationSalesAndMarketingExpense" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationSalesAndMarketingExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationInventoryWriteDown" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationInventoryWriteDown" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DeferredCompensationSharebasedArrangementsLiabilityRollForward" abstract="true" name="DeferredCompensationSharebasedArrangementsLiabilityRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_CronosIsraelG.S.StoreLtd.Member" abstract="true" name="CronosIsraelG.S.StoreLtd.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_A2020OmnibusPlanMember" abstract="true" name="A2020OmnibusPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_LoanReceivableNameAxis" abstract="true" name="LoanReceivableNameAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="cron_AltriaGroupInc.Member" abstract="true" name="AltriaGroupInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OtherNetAssetsLiabilities" abstract="false" name="OtherNetAssetsLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_MeasurementInputSubscriptionPriceMember" abstract="true" name="MeasurementInputSubscriptionPriceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OntarioIncMucciPromissoryNoteMember" abstract="true" name="OntarioIncMucciPromissoryNoteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_FinancingReceivableAccruedInterestCurrent" abstract="false" name="FinancingReceivableAccruedInterestCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FinancingReceivableBeforeAccruedInterestNoncurrent" abstract="false" name="FinancingReceivableBeforeAccruedInterestNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ClassOfWarrantOrRightExercisePriceVolumeWeightedAveragePriceMeasurementPeriodDaysPrecedingExercise" abstract="false" name="ClassOfWarrantOrRightExercisePriceVolumeWeightedAveragePriceMeasurementPeriodDaysPrecedingExercise" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cron_BuildingAndEquipmentMember" abstract="true" name="BuildingAndEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CronosIsraelG.S.ManufacturingLtd.Member" abstract="true" name="CronosIsraelG.S.ManufacturingLtd.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_AuditInformationAbstract" abstract="true" name="AuditInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardCliffPeriod" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardCliffPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cron_ProceedsFromDividends" abstract="false" name="ProceedsFromDividends" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationGoodwillImpairment" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationGoodwillImpairment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FinancingReceivableFaceAmount" abstract="false" name="FinancingReceivableFaceAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_NatuEraMember" abstract="true" name="NatuEraMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_ClassOfWarrantOrRightMinimumOwnershipPercentageRequired" abstract="false" name="ClassOfWarrantOrRightMinimumOwnershipPercentageRequired" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_IndefiniteLivedIntangibleAssetsAccumulatedImpairmentImpairmentInPeriod" abstract="false" name="IndefiniteLivedIntangibleAssetsAccumulatedImpairmentImpairmentInPeriod" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ConsultingServicesArrangementMember" abstract="true" name="ConsultingServicesArrangementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_EffectiveIncomeTaxRateReconciliationFairValueGainFinancialLiabilitiesAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationFairValueGainFinancialLiabilitiesAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationLeaseLiabilitiesCurrent" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationLeaseLiabilitiesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ShareBasedPaymentArrangementGainLossOnRevaluation" abstract="false" name="ShareBasedPaymentArrangementGainLossOnRevaluation" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_SensitivityAnalysisImpactOf10PercentDecreaseIncreaseInInterestRateOnInterestIncomeNet" abstract="false" name="SensitivityAnalysisImpactOf10PercentDecreaseIncreaseInInterestRateOnInterestIncomeNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CanadianPrimeRateMember" abstract="true" name="CanadianPrimeRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationRightOfUseAsset" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationRightOfUseAsset" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_StockIssuedDuringPeriodSharesShareBasedPaymentArrangement" abstract="false" name="StockIssuedDuringPeriodSharesShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="cron_GoodwillAndIntangibleAssetImpairmentIncludingDiscontinuedOperations" abstract="false" name="GoodwillAndIntangibleAssetImpairmentIncludingDiscontinuedOperations" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationOtherReceivables" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationOtherReceivables" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_IndefiniteLivedIntangibleAssetsAccumulatedImpairment" abstract="false" name="IndefiniteLivedIntangibleAssetsAccumulatedImpairment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FinancingReceivableBeforeAccruedInterestCurrent" abstract="false" name="FinancingReceivableBeforeAccruedInterestCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CronosGrowCoCreditFacilityMember" abstract="true" name="CronosGrowCoCreditFacilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_ManufacturingServicesMember" abstract="true" name="ManufacturingServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationGoodwillAndIntangibleAssetImpairment" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationGoodwillAndIntangibleAssetImpairment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ProceedsFromCollectionOfLoansOutstandingPrincipal" abstract="false" name="ProceedsFromCollectionOfLoansOutstandingPrincipal" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsForfeitureRate" abstract="false" name="SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsForfeitureRate" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_SensitivityAnalysisOfInterestRateRiskIncomeStatementImpactImpactOfChangeInAverageVariableRateOnInterestIncomePercent" abstract="false" name="SensitivityAnalysisOfInterestRateRiskIncomeStatementImpactImpactOfChangeInAverageVariableRateOnInterestIncomePercent" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_RealignmentMember" abstract="true" name="RealignmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OSCSettlementMember" abstract="true" name="OSCSettlementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_LongtermPurchaseCommitmentEquityInterestIssuedOrIssuableNumberOfShares" abstract="false" name="LongtermPurchaseCommitmentEquityInterestIssuedOrIssuableNumberOfShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="cron_InterestReceivedNet" abstract="false" name="InterestReceivedNet" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_ClassOfWarrantOrRightExercisePriceVolumeWeightedAveragePriceMeasurementPeriod" abstract="false" name="ClassOfWarrantOrRightExercisePriceVolumeWeightedAveragePriceMeasurementPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cron_FairValueRecurringBasisUnobservableInputReconciliationNetDerivativeAssetLiabilityGainLossStatementOfIncomeExtensibleListNotDisclosedFlag" abstract="false" name="FairValueRecurringBasisUnobservableInputReconciliationNetDerivativeAssetLiabilityGainLossStatementOfIncomeExtensibleListNotDisclosedFlag" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_EffectiveIncomeTaxRateReconciliationNondeductibleExpenseAcquisitionCostsAmount" abstract="false" name="EffectiveIncomeTaxRateReconciliationNondeductibleExpenseAcquisitionCostsAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationOperatingExpensesAbstract" abstract="true" name="DisposalGroupIncludingDiscontinuedOperationOperatingExpensesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_AssetHeldForSaleNotPartOfDisposalGroupSold" abstract="false" name="AssetHeldForSaleNotPartOfDisposalGroupSold" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_FinancingReceivableAccruedInterestNoncurrent" abstract="false" name="FinancingReceivableAccruedInterestNoncurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_RestructuringReservePaymentsAndWriteoffs" abstract="false" name="RestructuringReservePaymentsAndWriteoffs" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsWeightedAverageGrantDateFairValue" abstract="false" name="SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsWeightedAverageGrantDateFairValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:perShareItemType"/>
  <xs:element id="cron_PharmacannMember" abstract="true" name="PharmacannMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CBCALicensingAgreementMember" abstract="true" name="CBCALicensingAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_LongtermPurchaseCommitmentMonthlyFeePercentage" abstract="false" name="LongtermPurchaseCommitmentMonthlyFeePercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_IntangibleAssetsAccumulatedImpairmentTranslationAndPurchaseAccountingAdjustments" abstract="false" name="IntangibleAssetsAccumulatedImpairmentTranslationAndPurchaseAccountingAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DeferredCompensationShareBasedArrangementsTransferToEquityAwards" abstract="false" name="DeferredCompensationShareBasedArrangementsTransferToEquityAwards" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_HealthCanadaLicensingAgreementsMember" abstract="true" name="HealthCanadaLicensingAgreementsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CBCVALicensingAgreementMember" abstract="true" name="CBCVALicensingAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_IntangibleAssetsAccumulatedImpairment" abstract="false" name="IntangibleAssetsAccumulatedImpairment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DerivativeLiabilityUsefulLifeTerm" abstract="false" name="DerivativeLiabilityUsefulLifeTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cron_FacilityInStaynerOntarioCanadaMember" abstract="true" name="FacilityInStaynerOntarioCanadaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OtherInvestmentsRollForward" abstract="true" name="OtherInvestmentsRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_ConsultingServicesMember" abstract="true" name="ConsultingServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_AltriaInvestmentMember" abstract="true" name="AltriaInvestmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DeferredTaxAssetsFinanceLeaseLiabilities" abstract="false" name="DeferredTaxAssetsFinanceLeaseLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_AccumulatedImpairmentOfPropertyPlantAndEquipment" abstract="false" name="AccumulatedImpairmentOfPropertyPlantAndEquipment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_AltriaWarrantMember" abstract="true" name="AltriaWarrantMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CannabisFlowerMember" abstract="true" name="CannabisFlowerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationShareBasedCompensation" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationShareBasedCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CronosIsraelGSPharmacyLtdMember" abstract="true" name="CronosIsraelGSPharmacyLtdMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_FiniteLivedIntangibleAssetsAccumulatedImpairmentTranslationAndPurchaseAccountingAdjustments" abstract="false" name="FiniteLivedIntangibleAssetsAccumulatedImpairmentTranslationAndPurchaseAccountingAdjustments" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_LongtermPurchaseCommitmentPaymentsSubjectToMilestones" abstract="false" name="LongtermPurchaseCommitmentPaymentsSubjectToMilestones" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_UnitedStatesSegmentMember" abstract="true" name="UnitedStatesSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_OtherCountriesMember" abstract="true" name="OtherCountriesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationOtherIncomeLoss" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationOtherIncomeLoss" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_DerivativeInstrumentsRollForward" abstract="true" name="DerivativeInstrumentsRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cron_FacilityInLosAngelesCaliforniaMember" abstract="true" name="FacilityInLosAngelesCaliforniaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cron_StockIssuedDuringPeriodSharesResearchAndDevelopmentMilestones" abstract="false" name="StockIssuedDuringPeriodSharesResearchAndDevelopmentMilestones" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="cron_GreenLeafVsCronosMember" abstract="true" name="GreenLeafVsCronosMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_AltriaVenturesInc.Member" abstract="true" name="AltriaVenturesInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_CollaborativeArrangementAmountOfAdvances" abstract="false" name="CollaborativeArrangementAmountOfAdvances" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_CollaborativeArrangementProfitsToBeReceivedMaximumPercentageOfAmountsAdvanced" abstract="false" name="CollaborativeArrangementProfitsToBeReceivedMaximumPercentageOfAmountsAdvanced" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_DeferredShareUnitsDSUsMember" abstract="true" name="DeferredShareUnitsDSUsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_InvestmentOwnedPercentage" abstract="false" name="InvestmentOwnedPercentage" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types1:percentItemType"/>
  <xs:element id="cron_DisposalGroupIncludingDiscontinuedOperationRestructuringCosts" abstract="false" name="DisposalGroupIncludingDiscontinuedOperationRestructuringCosts" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_OtherCostOfGoodsAndServicesSold" abstract="false" name="OtherCostOfGoodsAndServicesSold" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cron_GinkoExclusiveLicensesMember" abstract="true" name="GinkoExclusiveLicensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
  <xs:element id="cron_GinkgoBioworksInc.Member" abstract="true" name="GinkgoBioworksInc.Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types1:domainItemType"/>
</xs:schema>
